Finding treatments and improving care for children and adults with a CASK disorder
What we do
CASK Research partners with clinicians and scientists to advance understanding and develop treatments for CASK-related disorders. Since 2022, UK research has grown from zero to at least five universities working towards targeted therapies — growth driven directly by the work of the CASK Research Foundation.
The CASK documentary
What is CASK?
CASK is the name of a gene essential for healthy development of the brain. Mutations in this gene cause a range of disorders that all affect brain function.
What is CASK? →Counting CASK
Help us know how many people in the world have a CASK disorder. Every registered patient makes clinical trials, treatments and care more achievable.
Register on Counting CASK →Don't speak English? Other languages are available on our CASK Registries page.
We can do this together
We have no government funding — all our funds come from community fundraisers and grants.
Support us →Latest news
Sept 2026
New Study funded! Do CASK changes make human brain cells less active, and can we safely boost that activity again?
Sept 2026
New Study for International Families
Sept 2026
Rowlands Castle dad takes on 200km static bike challenge
Aug 2026
New Study! Researching missense mutations in boys — personalised drug screening to find treatments
Stay in the loop
Monthly research breakthroughs, family stories and ways to help — straight to your inbox.
Supporting families
We bring families together through annual UK meet-ups, provide clear and accessible information about the disorder through dedicated booklets, and offer mental health support to families living with CASK-related conditions.
Find out more →
Our partnerships
We believe working together is the only way to move forwards.
Research
We fund and support vital research, including innovative gene therapy, animal models for drug screening, and studies exploring the full range of symptoms and behavioural impacts of CASK-related disorders.
Learn more →